Pre-clinical services

Biological Research Department
Provides Non-Animal pre-clinical research and testing for evaluating toxicity and efficacy.
Bio research Department has developed various in-vitro methods for claim substantiation of products to determine the efficacy and safety of products by pre-clinical assays.

The team has experience in in-vitro assay studies conducted worldwide, as well as in serving the testing needs of diverse industrial clients. Our familiarity with an array of different assay systems and product lines gives us the knowledge and expertise to determine the optimum assay for specific test materials and applications. We are NABL accredited and experienced in performing in-vitro procedures in compliance with Good Laboratory Practice (GLP).

Services under this are

EFFICACY MODELS

  • Skin lightening/Tanning
    • MelaninSynthesis Inhibition
    • Melanin Production Acceleration
    • Inhibition of Tyrosinase
    • UV protection assay using cell lines
  • Anti ageing
    • Anti Elastase assay
    • Anti Collagenase assay
    • Anti Hyaluronidase assay
    • Cell based assay for collagen enhancement
    • Antioxidant studies
  • Anti Inflammatory
    • TNF α
    • LTB4
    • NO radical
    • i NOS
  • Anti oxidant
    • DPPH radical scavenging activity
    • ORAC
    • HORAC
    • Inhibition of Lipid Peroxidation
    • Cell based inhibition of Reactive Oxygen Species (ROS)
  • Anti Obesity
    • Anti Lipase Assay
    • Cell based assay – Inhibition of Adipogenesis
  • Anti Diabetes
    • Alpha glucosidase inhibitory assay
    • DPP IV inhibitory assay
    • 11 β- Hydroxy Steroid Dehydrogenase type I (11 β HSD I) inhibitory assay
    • Neutral Endopeptidase (NEP) inhibitory assay
    • Protein Tyrosinase Phosphatase (PTP IB) inhibitory assay
  • Anti Microbial
    • S.aureus
    • S. epidermidis
    • E. coli
    • C.albicans
    • M.furfur
    • P.anes

SAFETY STUDIES

  • Dermal Irritection® Assay System
  • Ocular Irritection® Assay System
  • Cytotoxicity studies
  • Bacterial Reverse Mutational Assay
  • Others
    • Scratch Wound Closure Assay
    • Gluten assay
    • Cholestrol Ester Transfer Protein (CETP) inhibitory assay
 
 
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